Research Article:
Antibody Productivity of CHO Cells is Altered by ER Stress Tolerance of the Host Cell
Overview
This research article from AGC Biologics' R&D team in Japan compared high- and low-producing Chinese hamster ovary (CHO) cell clones of two types of antibodies to explore the factors involved in the antibody productivity.
This research includes comparison testing with:
- Cell line cultivation
- Digital droplet PCR
- Quantitative real-time PCR
- Proteomic analysis
This article was originally published with Gavin Publishers in March 2024.