Overview
This research article discusses the results of adding Tyr and Cystine to CHO cells and how they affected viability, growth, and mAb productivity due to endoplasmic reticulum (ER) stress and ER -associated degradation (ERAD).
Download the paper to read the full article.
This research includes:
- Study for CHO fed-batch culture for omics
- CHO batch culture with coenzyme Q10
- Transcriptomic and proteomic profiling of CHO cells
- Oxidative stress level analysis
This article was originally published with Biotechnology Journal in May 2023.